Services

The benefits of our technologies

While developing its nanomedicine pipeline, CARLINA Technologies focuses its activities on providing high quality R&D formulation development services to the pharmaceutical, veterinary and biotechnology industries utilizing both its proprietary controlled drug delivery platforms as well as its experience using many other systems including liposomes, micelles, microspheres, hydrogels, organogels, etc.

Examples of benefits provided by our technology platforms and know-how :

  • Solubilization, transport and targeting of poorly water-soluble drugs
  • Improved pharmacokinetics and duration of action of therapeutic proteins and peptides through sustained delivery
  • Use of non toxic GRAS/FDA approved excipients
  • Straightforward manufacturing processes avoiding the use of toxic organic solvents
  • Production of highly concentrated protein suspensions without denaturation

Non exhaustive list of therapeutic domains that can benefit from our technologies and know-how:

  • Diabetes
  • Cancer
  • Hemophilia
  • Anemia
  • Eye diseases (AMD, diabetic retinopathy)
  • Infectious deseases
  • Growth hormone deficiency
  • Hepatitis
  • Wound healing

Controlled delivery of a large number of pharmaceutical ingredients :

  • Small chemical entities
  • Peptides
  • Proteins (such as antibodies and their fragments)
  • Nucleic acids (DNA, RNA)
  • Contrast agents
Services - CARLINA Technologies - The benefits of our technologies

CARLINA Technologies also provides out-licensing/partnership opportunities on its preclinical stage product portfolio including

PEPTIDOTS-Insulin

A prolonged-release form of insulin

SOLUDOTS-PTX

A tumor-targeted paclitaxel-loaded nanoparticle

SOLUGEL-DAP

A sustained-release form of daptomycin

Industrial objectives

For each project, CARLINA Technologies takes industrial, economic and commercial requirements into consideration according to specific products and corresponding therapeutic applications. CARLINA’s expertise in project management allows rigourous development phase evaluation and control.

Sense of innovation

The creativity of CARLINA Technologies results from the complementarity and skills of its team members, acquired experience from diversified and complex projects as well as advanced competitive intelligence knowledge. This is the basis for bringing unique solutions as well as original innovation and valorization axes proposed to our clients and partners.

International recognized scientific expertise

Each study benefits from combined high level scientific input from international well recognized experts in the field of controlled drug delivery and high quality specific analytical equipments and methodologies (high performance liquid chromatography, dynamic light scattering, electron microscopy, electrophoretic mobility, etc.)

Process manufacturing

Following early laboratory scale production feasibility studies, CARLINA Technologies’ manufacturing processes allow rapid determination and validation of transposition conditions for successful product manufacturing at industrial scales.

Learn more about CARLINA Technologies